300 years from now wouldn't 90% of Bitcoins eventually end up being permanently lost?

It's basic math. Every year thousands of bitcoins are sent to the wrong addresses, owners with cold wallets die, and private keys are lost forever. Right now over 4 million bitcoins are estimated to be lost forever and every year that number rises. So eventually say 300-400 years from now if 90% of Bitcoins end up being permanently lost what happens to the network security if so little transactions are being performed? Wouldn't this decrease the hash rate by A LOT since miners wouldn't make a lot of money and would leave the space.